Ulcerative Colitis Medication

In a person with ulcerative colitis, diarrhea and cramping often improve as the inflammation improves. However, medication may also be necessary to treat these symptoms. Your healthcare provider may recommend a fiber supplement, or an antidiarrheal medicine. These drugs can include:
  • Diphenoxylate (Lomotil®)
  • Loperamide (Imodium®)
  • Codeine.
People who have severe ulcerative colitis should use these medicines with caution, since they can increase the risk of toxic megacolon, which is a potentially life-threatening condition.

Medications to Avoid

Some nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen (Motrin®, Advil®), can actually make the symptoms of ulcerative colitis worse. You should talk with your healthcare providers about which types of medication you should avoid, and about the possible side effects of any medication your doctor prescribes.
You should also talk with your healthcare provider before taking any vitamin or herbal supplements. It may be dangerous for some people with ulcerative colitis to take these drugs.

Information on Ulcerative Colitis

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