S. Food and Drug Administration (FDA) has approved the drug sulfasalazine (Azulfidine®) for the treatment of ulcerative colitis, a condition characterized by rectal bleeding, diarrhea, and other symptoms. Sulfasalazine is taken orally (by mouth), anywhere from three to six times a day.
This medication is thought to work by affecting the production of certain chemicals in the lining of the colon that cause the inflammation seen with ulcerative colitis. A delayed-release form is also available for the treatment of rheumatoid arthritis. Most people tolerate it well; however, side effects are possible, such as nausea, vomiting, and loss of appetite.
(To learn more about this oral medication, click Sulfasalazine. This article explains what to tell the healthcare provider prescribing it, what to do in cases of overdose, and more.)