Why Is Sulfasalazine Delayed-Release Used for Rheumatoid Arthritis?
There are many symptoms of rheumatoid
arthritis, including chronic pain, along with tender, warm, and swollen joints.
Sulfasalazine delayed-release is approved to treat these signs and symptoms.
Why Is Sulfasalazine Delayed-Release Used for Juvenile Rheumatoid Arthritis?
Juvenile rheumatoid arthritis is a form of rheumatoid arthritis that begins in childhood. With this condition, the immune system begins to attack the body (including the joints), causing pain. Other symptoms of juvenile rheumatoid arthritis include:
- Unexplained rashes
- Fever
- Swollen joints
- Tiredness.
Sulfasalazine delayed-release is approved to reduce the signs and symptoms of moderate to severe polyarticular juvenile rheumatoid arthritis. "Polyarticular" means that the arthritis affects five or more joints.
How Does Sulfasalazine Delayed-Release Work?
Sulfasalazine delayed-release belongs to a group of medications called aminosalicylates. It is thought that it works by inhibiting the production of inflammatory chemicals in the lining of the
colon. The medication decreases the production of prostaglandins and leukotrienes, chemicals that lead to the inflammation caused by
ulcerative colitis.
It is not fully understood exactly how sulfasalazine delayed-release works for rheumatoid arthritis and juvenile rheumatoid arthritis. However, it is thought that the medication likely decreases inflammation and affects the immune system.
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