What Is Sulfasalazine Delayed Release Used For?

Using Sulfasalazine Delayed-Release for Rheumatoid Arthritis
Rheumatoid arthritis is an autoimmune disease. This means that, for some reason, the immune system mistakes a person's own cells as invaders and attacks them, causing damage. Similar to other autoimmune diseases, scientists still do not know the causes of rheumatoid arthritis.
There are many symptoms of rheumatoid arthritis, including chronic pain, along with tender, warm, and swollen joints. Sulfasalazine delayed-release is prescribed treat these signs and symptoms.

Sulfasalazine Delayed-Release Uses for Juvenile Rheumatoid Arthritis

Juvenile rheumatoid arthritis is a form of rheumatoid arthritis that begins in childhood. With this condition, the immune system begins to attack the body (including the joints), causing pain. Other symptoms of juvenile rheumatoid arthritis include:
  • Unexplained rashes
  • Fever
  • Swollen joints
  • Tiredness.
Sulfasalazine delayed-release is approved to reduce the signs and symptoms of moderate to severe polyarticular juvenile rheumatoid arthritis. "Polyarticular" means that the arthritis affects five or more joints.

How Does It Work?

Sulfasalazine delayed-release belongs to a group of medications called aminosalicylates. It is thought that the medication works by inhibiting the production of inflammatory chemicals in the lining of the colon. Sulfasalazine delayed-release decreases the production of prostaglandins and leukotrienes, chemicals that lead to the inflammation caused by ulcerative colitis.
It is not fully understood exactly how sulfasalazine delayed-release works for rheumatoid arthritis and juvenile rheumatoid arthritis. However, it is thought that the medication likely decreases inflammation and affects the immune system.
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