Sulfasalazine Delayed Release Side Effects

Some of the most common side effects of sulfasalazine delayed-release include a loss of appetite, nausea or vomiting, and headaches. Fortunately, most people have no problems when taking the drug. Although many side effects are minor and easily treated, you should contact your healthcare provider right away if you develop more serious side effects, such as hallucinations, anemia, or depression.

Sulfasalazine Delayed-Release Side Effects: An Introduction

As with any medicine, side effects are possible with sulfasalazine delayed-release (Azulfidine EN-tabs®). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with sulfasalazine delayed-release. Your healthcare provider can discuss a more complete list of sulfasalazine delayed-release side effects with you. For more information, see Sulfasalazine Side Effects.)
 

Serious Side Effects of Sulfasalazine Delayed-Release

Some sulfasalazine delayed-release side effects, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Worsening of ulcerative colitis symptoms
  • Anemia
  • Depression
  • Hallucinations
  • Yellowing of the whites of the eyes or skin (jaundice)
  • Easy bruising or unusual paleness
  • Decreased urination or painful urination
  • Signs of an allergic reaction, including:
 
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 
(Sulfasalazine Delayed Release Side Effects Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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