Sulfasalazine Delayed Release Dosing

For the treatment of ulcerative colitis or rheumatoid arthritis with sulfasalazine delayed-release, dosing guidelines will vary based on several factors. Some of these factors include your age and weight, the condition being treated, other medical conditions you may have, and other medications you are taking. The sulfasalazine delayed-release dosage comes in tablet form, and is taken two to six times a day.

 

Sulfasalazine Delayed-Release Dosage: An Introduction

The dose of sulfasalazine delayed-release (Azulfidine EN-tabs®) that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • The medical condition being treated
  • Your age and weight
  • Other medical conditions you may have
  • Other medications you may be currently taking.
     
As is always the case, do not adjust your sulfasalazine delayed-release dose unless your healthcare provider specifically instructs you to do so (see Sulfasalazine Dosing for more information).
 

Sulfasalazine Delayed-Release Dosage for Active Ulcerative Colitis

The recommended starting dose of sulfasalazine delayed-release for cases of mild to moderately active ulcerative colitis in adults is sulfasalazine delayed-release 3000 mg to 4000 mg per day (divided into smaller doses taken at least every eight hours). For children age six and older, the recommended dose is sulfasalazine delayed-release 40 mg to 60 mg per kg (about 18 mg to 27 mg per pound) per day, divided into three to six smaller doses.
 
Your healthcare provider may decide to start you at a lower dose and slowly increase it, as this may decrease the risk of upset stomach and other intestinal-related sulfasalazine delayed-release side effects.
 
(Sulfasalazine Delayed Release Dosing Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;