Sulfasalazine Delayed Release Dosing

For the treatment of ulcerative colitis or rheumatoid arthritis, the dose of sulfasalazine delayed-release you are prescribed will be based on several factors. Some of these factors include your age and weight, the condition being treated, and other medications you are taking. The medication comes in tablet form, and is typically taken two to six times a day.

Sulfasalazine Delayed-Release Dosage: An Introduction

The dose of sulfasalazine delayed-release (Azulfidine EN-tabs®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The medical condition being treated
  • Your age and weight
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so (see Sulfasalazine Dosing for more information).

What Is the Dose for Active Ulcerative Colitis?

The recommended starting sulfasalazine delayed-release dosage for cases of mild to moderately active ulcerative colitis in adults is 3000 mg to 4000 mg per day (divided into smaller doses taken at least every eight hours). For children age six and older, the recommended dose is 40 mg to 60 mg per kg (about 18 mg to 27 mg per pound) per day, divided into three to six smaller doses.
Your healthcare provider may decide to start you at a lower dose of sulfasalazine delayed-release and slowly increase it, as this may decrease the risk of upset stomach and other intestinal-related side effects.

Dosing for Ulcerative Colitis That Is in Remission

Once your ulcerative colitis is in remission, your healthcare provider may decrease your dose to sulfasalazine delayed-release 2000 mg daily (divided into several smaller doses) for adults. For children age six and up, the dose can be reduced to 30 mg per kg (about 13.5 mg per pound) per day, divided into four smaller doses.
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Sulfasalazine Delayed-Release Drug Information

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