Drug Interactions With Sulfasalazine Delayed-Release

Potentially negative drug interactions can occur when certain medications are taken together. Medicines that can interact with sulfasalazine delayed-release include warfarin, folic acid, and digoxin. These interactions may lead to a decreased effectiveness of the medicines. If sulfasalazine delayed-release drug interactions are a concern, your healthcare provider may adjust your doses as necessary.

Sulfasalazine Delayed-Release Drug Information

Sulfasalazine Delayed-Release Interactions: An Introduction

Sulfasalazine delayed-release (Azulfidine EN-tabs^®) can potentially interact with a few other medicines. Some of the medicines that may lead to drug interactions with sulfasalazine delayed-release include:

Digoxin (Digitek^®, Lanoxin^®)
Folic acid
Warfarin (Coumadin^®, Jantoven^®).

More Information on Interactions With Sulfasalazine Delayed-Release

The following sections explain in detail the potentially negative interactions that can occur when sulfasalazine delayed-release is combined with any of the drugs listed above.

Digoxin

Sulfasalazine delayed-release may decrease the absorption of digoxin into your body, perhaps making it less effective. Your healthcare provider should monitor the level of digoxin in your blood, especially when you are starting or stopping sulfasalazine delayed-release.

Folic Acid

Sulfasalazine delayed-release may decrease the absorption of folic acid into your body. Ask your healthcare provider about taking folic acid supplements, especially if you are a woman of childbearing age.

Warfarin

Sulfasalazine delayed-release may interact with warfarin. Your healthcare provider should monitor you more closely and adjust your warfarin dosage as necessary to prevent this interaction from occurring.

(Drug Interactions With Sulfasalazine Delayed-Release Continued: Page 2)