Rowasa Drug Interactions

When certain medications are taken together with Rowasa, drug interactions can potentially occur that could lead to a reduced effectiveness of the medicines. If you take warfarin or digoxin with Rowasa, your healthcare provider may need to monitor the levels of the drugs in your blood. To minimize the risk of developing Rowasa drug interactions, make sure to talk with your healthcare provider or pharmacist about any interactions that may apply to you.

 

An Introduction to Rowasa Drug Interactions

Rowasa® (mesalamine) can potentially interact with a few other medicines. Among these medicines that may lead to Rowasa interactions are:
 
  • Digoxin (Digitek®, Lanoxin®)
  • Warfarin (Coumadin®, Jantoven®).
     

Rowasa Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Rowasa is combined with any of the drugs listed above.
 
Digoxin (Digitek, Lanoxin)
Rowasa may decrease the absorption of digoxin into your body, perhaps making it less effective. Because very little Rowasa is absorbed into the bloodstream, this interaction is less likely (but still possible). If you are taking these drugs together, your healthcare provider may need to monitor the level of digoxin in your blood -- especially when you are starting or stopping Rowasa.
 
Warfarin (Coumadin, Jantoven)
There have been a few reports of Rowasa making warfarin less effective. Because very little Rowasa is absorbed into the bloodstream, this interaction is less likely (but still possible). If you are taking these drugs together, your healthcare provider may need to monitor you more closely and adjust your warfarin dosage as necessary.
 
(Rowasa Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;