Drug Interactions With Natalizumab
More Detail on Drug Interactions With NatalizumabThe following sections explain in detail the potentially negative reactions that can occur when natalizumab is combined with any of the drugs listed above.
In general, people receiving natalizumab should not take immunosuppressants, due to an increased risk for potentially serious side effects, including infections. People who take corticosteroids should be taken off the corticosteroid within six months of starting natalizumab.
Combining leflunomide with natalizumab may increase your risk for side effects, such as low red blood cells, white blood cells, and platelets. These reactions could lead to anemia, infections, or bleeding problems. Your healthcare provider will likely monitor you for these problems if you use these medications together.
Live vaccines are vaccines that contain live viruses or bacteria. If you receive a live vaccine while using natalizumab, you might become infected with the virus or bacteria from the vaccine. Also, live vaccines may be less effective in people receiving natalizumab. Talk to your healthcare provider before receiving a vaccination or immunization while using this medication.
Combining natalizumab with sipuleucel-T can make sipuleucel-T less effective. Talk to your healthcare provider before using these medicines together.