Colitis Home > Uceris Uses

How Does It Work?

Uceris is a corticosteroid. It works by decreasing inflammation, which is one of the problems in ulcerative colitis. Steroids are often needed to help people control flares (temporary worsenings) of ulcerative colitis. However, unlike most other steroids, Uceris is less likely to cause the typical steroid side effects, which can be quite bothersome or serious.
 
Uceris tablets are uniquely designed with both an enteric coating and extended-release properties. The enteric coating is designed to dissolve only in the intestine (not in the stomach), after which the tablet will slowly release the medication throughout the colon. As an added advantage, when Uceris is absorbed into the body, the liver changes most of it into other compounds that do not have steroid side effects. Uceris works mostly when it comes into contact with the colon; therefore, it does not need to circulate throughout the body to work. 
 

Is It Safe for Children to Use Uceris?

This drug is not approved for use in children or adolescents, as it has not been adequately studied in these age groups. Talk with your child's healthcare provider about the benefits and risks of using Uceris in children.
 

Off-Label Uses for Uceris

On occasion, your healthcare provider may recommend this medication for something other than its approved use. This is called an "off-label" use. At this time, using Uceris for ulcerative colitis maintenance treatment (for longer than eight weeks) is an off-label use.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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