Colitis Home > What Is Sulfasalazine Used For?

How Does Sulfasalazine Work?

Sulfasalazine belongs to a group of medications called aminosalicylates. It is thought that the drug works by inhibiting the production of inflammatory chemicals in the lining of the colon. Sulfasalazine decreases the production of prostaglandins and leukotrienes, chemicals that lead to the inflammation caused by ulcerative colitis.

Is Sulfasalazine Used for Children?

Sulfasalazine is approved for treating ulcerative colitis in children ages six and up. Be sure to talk with your healthcare provider about the risks and benefits of using the drug in children.

Is Sulfasalazine Used for Off-Label Purposes?

On occasion, your healthcare provider may recommend sulfasalazine for treating something other than ulcerative colitis. This is called an "off-label" use. At this time, off-label sulfasalazine uses include the treatment of:
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Last reviewed by: Kristi Monson, PharmD;
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