Colitis Home > Pentasa Warnings and Precautions

It's important to understand Pentasa warnings and precautions before starting the medication. For example, Pentasa may cause kidney and liver damage. If you have liver or kidney disease, let your healthcare provider know before taking the drug. Pentasa warnings and precautions also extend to people with certain allergies and women who are pregnant or breastfeeding.

Pentasa: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Pentasa® (mesalamine) if you have:
  • Liver disease, including liver failure or cirrhosis
  • Kidney disease, including kidney failure (renal failure)
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Be sure to tell your healthcare provider about all medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Pentasa Warnings and Precautions

Some warnings and precautions to be aware of prior to taking Pentasa include the following:
  • The medication may cause a worsening of ulcerative colitis. Be sure to tell your healthcare provider if your ulcerative colitis symptoms become worse when you start taking Pentasa.
  • Pentasa may cause kidney damage. Your healthcare provider should check your kidney function (using a blood test) before you start treatment and again periodically thereafter. You should not take Pentasa if you have kidney disease, including kidney failure (renal failure).
  • The medication may cause liver damage. Talk to your healthcare provider before taking Pentasa if you have liver disease, including liver failure or cirrhosis.
  • Pentasa is considered a pregnancy Category B medication. This means that it is probably safe for pregnant women, although the full risks are not known. Be sure to talk to your healthcare provider about the risks and benefits of taking the drug while pregnant (see Pentasa and Pregnancy).
  • Pentasa passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before taking the drug (see Pentasa and Breastfeeding).
  • Pentasa can interact with certain medications (see Pentasa Drug Interactions).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.