Colitis Home > Pentasa Drug Interactions

If certain medications are taken with Pentasa, drug interactions may occur that have potentially negative consequences. For example, if warfarin or digoxin are combined with Pentasa, the medications' effectiveness may be decreased. If Pentasa drug interactions are a concern, your healthcare provider may monitor you more closely, using blood tests, or adjust your dosages.

Pentasa Drug Interactions: An Overview

Pentasa® (mesalamine) can potentially interact with a few other medicines. Some of the medicines that may lead to Pentasa drug interactions include:
 

Pentasa Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Pentasa is combined with any of the drugs listed above.
 
Digoxin
Pentasa may decrease the absorption of digoxin into your body, perhaps making it less effective. Your healthcare provider should monitor the level of digoxin in your blood, especially when you are starting or stopping Pentasa.
 
Warfarin
There have been a few reports of Pentasa making warfarin less effective. Your healthcare provider should monitor you more closely and adjust your warfarin dosage as necessary to prevent interactions from occurring.
 

Final Thoughts on Pentasa Drug Interactions

It is possible that not all Pentasa drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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