Colitis Home > Infliximab Side Effects

Commonly reported side effects of infliximab include infections, headaches, and anemia. While most people tolerate the drug without problems, if side effects occur, they are often minor and easily treated. However, some side effects are potentially serious and should be reported immediately to your healthcare provider, including dark urine, difficulty breathing, or seizures.

An Introduction to Infliximab Side Effects

As with any medicine, side effects are possible with infliximab (Remicade®). However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can be treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with infliximab. Your healthcare provider can discuss a more complete list of infliximab side effects with you.)

Serious Side Effects of Infliximab

Some side effects with infliximab, while occurring infrequently, are potentially serious and should be reported to your healthcare provider. These include but are not limited to:
  • Symptoms of an infection, such as:
    • Coughing
    • Chills
    • Fever
    • Weakness
  • Signs of liver damage, such as:
    • Dark urine
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Upper abdominal pain (stomach pain)
  • Difficulty breathing, especially accompanied by water retention or swelling, which may be signs of congestive heart failure (CHF)
  • A seizure  
  • Signs of low blood pressure, including dizziness, lightheadedness, or fainting
  • Unusual skin or mole changes (possible signs of skin cancer)
  • Unexplained bruising or bleeding
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Wheezing or difficulty breathing
    • Unexplained swelling.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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