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Effects of Humira

The medication has been studied in several clinical trials for the following conditions:
Ankylosing Spondylitis
Clinical studies have shown that Humira is effective at improving the symptoms of ankylosing spondylitis, including back pain and morning stiffness. People taking Humira showed greater improvements in their symptoms of ankylosing spondylitis, compared to those not taking it.
Crohn's Disease
Humira was also studied for treating Crohn's disease. In one study, up to 58 percent of those taking it showed significant improvement in their Crohn's disease symptoms, compared to just 34 percent of those not taking it. Humira also increased the chance of remission and helped keep the symptoms of Crohn's disease from returning.
Juvenile Idiopathic Arthritis
In studies, children with juvenile idiopathic arthritis who were given Humira with or without methotrexate (Rheumatrex®, another medication) were less likely to have a disease flare, compared to children who were not given Humira.
Plaque Psoriasis
In one study, up to 71 percent of people who were treated with Humira for 16 weeks for plaque psoriasis had "clear" or "minimal" disease, compared to just 10 percent of people who were not given it.
Psoriatic Arthritis
In a study of Humira for psoriatic arthritis, the medication was shown to reduce pain and other psoriatic arthritis symptoms, including joint stiffness. Also, it helped to lessen the physical joint changes of psoriatic arthritis, compared to those not taking it.
Rheumatoid Arthritis
In clinical studies looking at Humira as a rheumatoid arthritis treatment, the drug was shown to improve the symptoms of rheumatoid arthritis. More of the people taking Humira showed improvement compared to the people not taking it. The medication also improved the physical joint changes that occur with rheumatoid arthritis.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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