Entocort EC is a medication that is licensed for the treatment of Crohn's disease. As a type of corticosteroid, it works by decreasing inflammation in the intestines. The medication, which is only available by prescription, comes in the form of a capsule that is generally taken once a day in the morning. Potential side effects include headaches, respiratory infections, and nausea.
(Click Entocort Uses for more information on what the medication is used for, including possible off-label uses.)
Who Makes It?
Entocort EC is manufactured by AstraZeneca and distributed by Prometheus Laboratories, Inc.
How Does It Work?
Entocort EC is a corticosteroid. It works by decreasing inflammation (one of the problems in Crohn's disease). Steroids are often needed to help people control flares of Crohn's disease (when the symptoms temporarily get worse). However, unlike most other steroids, Entocort EC is less likely to cause the typical side effects of steroids (which can be quite bothersome and serious).
This medication is specifically designed to be released in the intestine (not in the stomach). When the medication is absorbed into the body, the liver changes most of it into other compounds that do not have steroid side effects. Entocort EC mostly works when it comes in contact with the intestines; therefore, it does not need to circulate throughout the body to work.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed August 2, 2011.
AstraZeneca. AstraZeneca reaches US agreement With Teva Pharmaceuticals regarding Entocort EC capsules (5/18/2010). AstraZeneca Web site. Available at: http://www.astrazeneca.com/media/latest-press-releases/Teva-Pharmaceuticals-Agreement-Entocort?itemId=9427564. Accessed June 4, 2010.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed November 30, 2007.
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