Colitis Home > Asacol Dosage

For those who are treating mild-to-moderately-active ulcerative colitis with Asacol, dosing typically starts at two 400 mg tablets three times a day for six weeks. Once your condition is in remission, your healthcare provider may choose to decrease your daily Asacol dose to four tablets, taken in separate doses. Make sure to take your Asacol dosage at the same times each day to maintain even levels of the medicine in your blood.

In 2013, Asacol 400 mg tablets were removed from the market and replaced with Delzicol 400 mg capsules. Please see Delzicol for up-to-date information.  

An Introduction to Asacol Dosage

The dose of Asacol® (mesalamine) that your healthcare provider recommends will vary depending on a number of factors, including:
  • The severity of your condition
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As always, do not adjust your Asacol dosage unless your healthcare provider specifically instructs you to do so.
Asacol Dosing for Active Ulcerative Colitis
The recommended starting Asacol dose for adults with mild-to-moderately active ulcerative colitis is two Asacol 400 mg tablets three times daily (for a total of 2400 mg or 2.4 grams daily) for six weeks.
For children age five and up, your healthcare provider will calculate an appropriate dosage using your child's weight. The medication is taken twice daily for six weeks. 
Asacol Dosing for Ulcerative Colitis Remission
For adults, once your ulcerative colitis is in remission, your healthcare provider may decrease your dose to Asacol 1600 mg (four tablets) daily in divided doses (such as one tablet four times daily or two tablets twice daily).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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