Colitis Home > Asacol HD Side Effects
Headaches, nausea, and common cold symptoms are the most common side effects that have been reported with Asacol HD. In most cases, side effects of the medicine are mild and, typically, do not require medical attention. However, certain side effects are potentially serious and should be reported to your healthcare provider immediately, including jaundice, urinary changes, or difficult breathing.
As with any medicine, side effects are possible with Asacol HD® (mesalamine). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Asacol HD. Your healthcare provider can discuss a more complete list of Asacol HD side effects with you.)
Asacol HD has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking Asacol HD were documented and compared to side effects that occurred in a similar group of people taking regular-strength Asacol (a lower dosage). This way, it is possible to see what side effects occurred, how often they appeared, and how they compare to the group taking regular Asacol. In general, the side effects were similar between the two drugs.
In these studies, the most common Asacol HD side effects included:
- Headaches -- in up to 4.7 percent of people
- Nausea -- up to 2.8 percent
- Common cold symptoms -- up to 2.5 percent
- Abdominal pain (stomach pain) -- up to 2.3 percent
- Worsening of ulcerative colitis -- up to 2.3 percent.
Other common side effects of Asacol HD (occurring in 1 to 2 percent of people) included, but were not limited to: