Colitis Home > Apriso Warnings and Precautions

If you have liver or kidney disease, you should tell your healthcare provider before starting Apriso. Precautions and warnings for the medication should also be reviewed with your healthcare provider in order to help minimize risks. Apriso is not suitable for everyone; you should not take it if you are allergic to salicylate medicines or any active (or inactive) ingredients used to make Apriso.

What Should I Tell My Healthcare Provider Before Taking Apriso?

You should talk with your healthcare provider prior to taking Apriso™ (mesalamine) if you have:
  • Kidney disease, including kidney failure (renal failure)
  • Liver disease, including liver failure, hepatitis, or cirrhosis
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
Be sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings for Apriso

Some warnings and precautions to be aware of with Apriso include:
  • Apriso may cause a worsening of ulcerative colitis. Be sure to tell your healthcare provider if your ulcerative colitis symptoms worsen when you start taking Apriso.
  • Apriso may cause kidney damage. Your healthcare provider should check your kidney function (using a blood test) before you start Apriso and periodically thereafter. Apriso may not be a good choice for you if you have kidney disease, including kidney failure (or renal failure).
  • Apriso may cause liver damage, particularly in people who already have liver disease. Talk to your healthcare provider before taking Apriso if you have liver disease, including liver failure or cirrhosis.
  • Apriso can interact with certain medications (see Apriso Drug Interactions).
  • Apriso is considered a pregnancy Category B medication. This means that it is probably safe for pregnant women, although the full risks are not known. Be sure to talk to your healthcare provider about the risks and benefits of using Apriso during pregnancy (see Apriso and Pregnancy).
  • Apriso passes through breast milk. Therefore, if you are breastfeeding or plan to start, be sure to talk with your healthcare provider about using Apriso (see Apriso and Breastfeeding for more information).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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