Infliximab for Ulcerative Colitis

Available by prescription only, infliximab (Remicade®) is a medicine used to treat several inflammatory conditions, including ulcerative colitis. This disease is a type of inflammatory bowel disease (IBD).
 
Although it is not a cure for ulcerative colitis, infliximab is approved to reduce the signs and symptoms of this disease and may even cause a remission for some people. This medication can also allow people to stop taking steroids for this condition.
 
As part of a class of drugs known as tumor necrosis factor inhibitors, or TNF inhibitors for short, infliximab works by blocking the activity of tumor necrosis factor-alpha (TNF-alpha). TNF-alpha is a naturally occurring chemical in the body that is involved in inflammation and other immune system functions.
 
People with ulcerative colitis often have higher levels of TNF-alpha. These high levels can cause inflammation and lead to problems. By blocking TNF-alpha, infliximab helps to relieve the symptoms of these conditions and, in some cases, prevents future damage from occurring.
 
(For more information on using this medication for ulcerative colitis, click What Is Infliximab Used For?. This article also discusses how infliximab works for treating other inflammatory conditions, as well as possible off-label uses of the drug.)
 
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