Infliximab Dosing

Dose for Rheumatoid Arthritis

The recommended dose for rheumatoid arthritis is infliximab 3 mg per kg (about 1.3 mg per pound) given intravenously (by IV). Your next two doses should be given two and six weeks after the first dose. After that, the doses should be given every eight weeks. If necessary, your healthcare provider may increase your dose, up to infliximab 10 mg per kg (about 4.5 mg per pound) every eight weeks. However, the maximum dose for people with moderate to severe heart failure (for any use) is 5 mg per kg (2.3 mg per pound) per dose.

General Information on Dosing With Infliximab

Considerations for people taking infliximab include the following:
  • Infliximab is given intravenously (by IV). Depending on the condition being treated, the medication is usually given more frequently at the beginning of treatment, followed by doses every six to eight weeks.
  • It will take at least two hours to administer each dose of infliximab by IV. These intravenous infusions are usually given at your healthcare provider's office or at an infusion center designed for people who need regular IV medications.
  • When used for rheumatoid arthritis, infliximab is intended to be taken with methotrexate, another medication that can be taken either by mouth or by injection.
  • If you are unsure about anything related to infliximab or infliximab dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
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Infliximab Drug Information

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