Infliximab and Crohn's Disease

 Infliximab (Remicade®) is a prescription drug approved to treat a wide variety of conditions associated with inflammation that affect the joints, skin, and digestive system. Crohn's disease is one of the conditions infliximab can treat. Not only does it help reduce the signs and symptoms of Crohn's disease -- it also helps reduce the number of fistulas that develop with this condition.
 
When used to treat Crohn's disease, infliximab works by blocking the activity of tumor necrosis factor-alpha (TNF-alpha). TNF-alpha is a naturally occurring chemical in the body that is involved in inflammation and other immune system functions. Although this medication is not a cure for Crohn's, it certainly goes a long way in relieving symptoms.
 
(To learn more about treating Crohn's disease with infliximab, click What Is Infliximab Used For?. This article explains in more detail how this drug works, other conditions it can treat, and whether children can take it.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD