How Does Infliximab Work?

Infliximab (Remicade®) belongs to a class of drugs called tumor necrosis factor inhibitors, or TNF inhibitors for short. These medications work by keeping the immune system from attacking the body. As the name implies, infliximab blocks the activity of tumor necrosis factor-alpha (TNF-alpha). TNF-alpha is a naturally occurring chemical in the body that is involved in inflammation and other immune system functions.
Higher levels of TNF are often found in people with rheumatoid arthritis, psoriasis, ankylosing spondylitis, ulcerative colitis, or Crohn's disease. These high levels can cause inflammation and lead to problems. Infliximab blocks TNF-alpha, thereby minimizing symptoms of these conditions -- and in some cases, even preventing future damage from occurring.
(Click Infliximab for more details on how the drug works. This article also provides information on side effects, how the medication performed in clinical trials, and more.)
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