Drug Interactions With Infliximab

Interactions With Infliximab Explained

The following sections explain in detail the potentially negative interactions that can occur when infliximab is combined with any of the drugs listed above.
 
Abatacept
Taking infliximab with abatacept can increase your risk of infection. In general, these two medications should not be taken together.
  
Anakinra
Combining infliximab with anakinra can increase your risk of infection. In general, these two medications should not be taken together.
 
Azathioprine
There have been reports of a very aggressive and fatal form of cancer known as hepatosplenic T-cell lymphoma in people who took infliximab with azathioprine, especially in young males being treated for Crohn's disease or ulcerative colitis. You and your healthcare provider should carefully discuss this risk before combining these two medications.
  
Etanercept
Taking infliximab with etanercept can increase your risk of infection. In most cases, these two medications should not be taken together.
 
Live Vaccines
As you might expect, live vaccines are immunizations that contain live viruses or bacteria. If you receive a live vaccine while taking infliximab, you might become infected with the virus or bacteria from the vaccine. Also, infliximab can make live vaccines less effective. You should not receive live vaccinations while taking this drug.
 
Mercaptopurine
There have been reports of a very aggressive and fatal form of cancer known as hepatosplenic T-cell lymphoma in people who took infliximab with mercaptopurine, especially in young males being treated for Crohn's disease or ulcerative colitis. You and your healthcare provider should carefully discuss this risk before combining these two medications.
  
Tocilizumab
Combining infliximab with tocilizumab may increase your risk of infection. In general, the combination of these two should be avoided.
  
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Infliximab Drug Information

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