Humira Uses

How Humira Works

Humira is part of a class of medicines known as tumor necrosis factor inhibitors, or TNF inhibitors for short. As the name of the drug class implies, Humira blocks the activity of tumor necrosis factor-alpha (TNF-alpha). TNF-alpha is a naturally occurring chemical in the body that is involved in inflammation and other immune system functions.
People with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, or Crohn's disease often have higher levels of TNF. These high levels of TNF-alpha can cause inflammation and lead to problems. By blocking TNF-alpha, Humira helps to relieve the symptoms of these conditions and, in some cases, prevents future damage from occurring.

Humira Use in Children

Humira is approved for treating juvenile idiopathic (rheumatoid) arthritis in children age four years and older, but it is not approved for any other use in children. Talk with your healthcare provider about the benefits and risks of using Humira in children.

Off-Label Humira Uses

On occasion, your healthcare provider may recommend Humira for something other than the conditions discussed above. This is called an "off-label" use. At one time, using Humira to treat plaque psoriasis or ulcerative colitis were considered off-label uses, and you will still find information on the Internet stating that they are off-label uses. However, since Humira is now approved for plaque psoriasis and ulcerative colitis, these are no longer off-label uses but approved uses.
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Humira Medication Information

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