How Does Colazal Work?

Colazal® (balsalazide disodium) is approved to treat the symptoms of ulcerative colitis in adults and children over the age of five. It comes in capsule form and is generally taken three times a day.
How does it work? Colazal is thought to decrease the production of certain chemicals in the lining of the colon. By targeting these inflammatory chemicals, the medicine helps to lessen symptoms caused by ulcerative colitis, such as abdominal pain (stomach pain) and rectal bleeding. In order for the drug to work properly, however, it should be taken at the same times each day.
It's important to note that the actual Colazal molecule is inactive. Bacterial enzymes split the molecule when it reaches the colon; this is where the medication is released.
(To learn more about how this drug works, click Colazal. This article explains the uses and effects of Colazal, and also provides an overview of side effects, safety issues to be aware of, and overdose information.)
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