How Does Canasa Work?

If you have ulcerative proctitis (a form of ulcerative colitis that affects just the rectum), your healthcare provider may recommend an aminosalicylate drug called Canasa® (mesalamine). The medicine comes in the form of a suppository and is generally used once a day before bedtime.
How does Canasa work? The medication is believed to work in the colon, slowing down the production of two types of chemicals (leukotrienes and prostaglandins) in the lining of the colon. These chemicals are associated with the inflammation caused by ulcerative colitis.
(To learn more about how this drug works, click Canasa. This article describes the medication in greater detail, with information on how to use it, potential side effects, "off-label" uses, and more.)
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