Azulfidine Warnings and Precautions

In order to ensure a safe treatment process, it is important to review the warnings and precautions of any medication you're about to take. With Azulfidine, this includes watching out for certain drug interactions and knowing about the possibility of developing anemia, kidney stones, or fertility problems (in men). Warnings and precautions with Azulfidine also extend to people who are allergic to any active or inactive components of the drug.

What Should I Tell My Healthcare Provider Before Taking Azulfidine?

You should talk with your healthcare provider prior to taking Azulfidine® (sulfasalazine) if you have:
 
  • Difficulty passing urine
  • An intestinal blockage
  • Porphyria (problems with certain enzymes in the body)
  • Kidney disease, including kidney failure (renal failure)
  • Liver disease, including liver failure or cirrhosis
  • Anemia or any other low blood cell count
  • Asthma
  • Any allergies, including allergies to sulfa drugs, food, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Be sure to tell your healthcare provider about all medicines you are currently taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

Specific Warnings and Precautions

Warnings and precautions to be aware of prior to taking Azulfidine include the following:
 
  • The medication may not be safe to use in people with severe asthma or allergies, kidney disease, liver disease, or anemia (or any other low blood counts). Be sure to tell your healthcare provider if you have any of these conditions before starting treatment.
     
  • Azulfidine can cause low sperm count and infertility in men, although fertility usually returns after the medication is stopped.
     
  • Be sure to drink plenty of fluids while taking Azulfidine, as this will help protect your kidneys and can help prevent kidney stones.
     
  • Your healthcare provider should regularly check your blood counts while you are taking the drug to make sure that you are not developing anemia or other serious problems.
     
  • Azulfidine is considered a pregnancy Category B medication. This means that the drug is probably safe for pregnant women, although the full risks are not known. Be sure to talk to your healthcare provider about the risks and benefits of using the drug while pregnant (see Azulfidine and Pregnancy).
     
  • Azulfidine passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before taking the drug (see Azulfidine and Breastfeeding).
     
  • Azulfidine can interact with certain medications (see Azulfidine Drug Interactions).
     
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Azulfidine Medication Information

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