Azulfidine® (sulfasalazine) is generally considered safe, but some people do experience side effects during treatment. Some of the most commonly reported ones include nausea, headache, and loss of appetite, among others.
To make sure you are tolerating the medication well, your healthcare provider should regularly check your blood counts while you are taking it to make sure you are not developing anemia or other serious problems.
Although most people are able to take Azulfidine safely, it is not a good choice for certain people. For example, you should not take this medication if you:
- Are allergic to any of the drug's ingredients
- Have an intestinal blockage
- Are allergic to aspirin or "sulfa drugs."
(For more safety information, click Azulfidine Warnings and Precautions and Azulfidine Side Effects. These articles tell you what you need to know before taking this medication, including details on how often side effects occurred in clinical trials.)