Drug Interactions With Azathioprine

Some azathioprine drug interactions can cause an increased risk of blood clots, anemia, or low levels of white blood cells, and can make certain medications less effective. Several drugs can interact negatively with azathioprine, such as ACE inhibitors, warfarin, and aminosalicylates. If you are experiencing drug interactions, your healthcare provider may adjust your dosages or monitor you more closely.

 

Azathioprine Interactions: An Introduction

Azathioprine (Imuran®) can potentially interact with a few other medicines. Some of the medicines that may lead to azathioprine drug interactions include:
 
 
 
  • Angiotensin-converting enzyme inhibitors (ACE inhibitors), including:
 
 
  • Sulfamethoxazole and trimethoprim (Bactrim®, Cotrim®, Septra®, Sulfatrim®)  
  • Warfarin (Coumadin®, Jantoven®).
     
(Drug Interactions With Azathioprine Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;