Azathioprine Dosing (Cont.)

Azathioprine Dosing for Rheumatoid Arthritis

The recommended starting dose of azathioprine for rheumatoid arthritis treatment is azathioprine 1 mg per kg (about 0.45 mg per pound) per day, usually between 50 mg to 100 mg per day. It can be taken once daily or split up into two doses per day. After eight weeks, your healthcare provider may increase your dose, if necessary.
 

General Information on Dosing With Azathioprine

Considerations for people taking azathioprine include the following:
 
  • The medication comes in tablet form. It is usually taken by mouth once or twice a day.
     
  • You can take azathioprine with or without food. If the medication bothers your stomach, try taking it with food.
     
  • Azathioprine should be taken at the same time(s) each day to maintain an even level in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. Azathioprine will not work if you stop taking it.
     
  • If you are unsure about anything related to azathioprine or azathioprine dosing, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;