Asacol Drug Interactions

If you take digoxin or warfarin with Asacol, drug interactions may potentially occur. These drug interactions with Asacol can decrease the effectiveness of digoxin or warfarin, and your healthcare provider may need to adjust your dosages of these medicines as necessary.

 

An Overview of Asacol Drug Interactions

Asacol® (mesalamine) can potentially interact with a few other medicines. Among these medicines that may lead to Asacol interactions are:
 
  • Digoxin (Digitek®, Lanoxin®)
  • Warfarin (Coumadin®, Jantoven®).
     

Asacol Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Asacol is combined with any of the drugs listed above.
 
Digoxin (Digitek, Lanoxin)
Asacol may decrease the absorption of digoxin into your body, perhaps making it less effective. If you are taking these drugs together, your healthcare provider should monitor the level of digoxin in your blood -- especially when you are starting or stopping Asacol.
 
Warfarin (Coumadin, Jantoven)
There have been a few reports of Asacol making warfarin less effective. If you are taking these drugs together, your healthcare provider should monitor you more closely and adjust your warfarin dosage as necessary.
 

Final Thoughts on Asacol Drug Interactions

It is possible that not every drug interaction with Asacol was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about Asacol drug interactions that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;