Asacol HD

Asacol HD is an extended-release medication often prescribed for the treatment of moderately active ulcerative colitis. It comes in tablet form and is typically taken three times a day for six weeks. The medicine is thought to work by inhibiting the production of inflammatory chemicals in the lining of the colon. Potential side effects include headache, nausea, and abdominal pain.

What Is Asacol HD?

Asacol HD® (mesalamine) is a prescription medication approved to treat moderately active ulcerative colitis (UC).
(Click Asacol HD Uses for more information, including information about possible off-label uses.)

Who Makes Asacol HD?

This medication is made by Warner Chilcott (US), LLC.

How Does Asacol HD Work?

Asacol HD belongs to a group of medications called aminosalicylates. It is thought to work by inhibiting the production of inflammatory chemicals in the lining of the colon. Asacol HD decreases the production of prostaglandins and leukotrienes, chemicals that lead to the inflammation of ulcerative colitis.
Asacol HD tablets have a special delayed-release coating. The coating prevents the tablets from dissolving until they reach the very end of the small intestine.

When and How Do I Take It?

Considerations for people taking this drug include the following:
  • The medication comes as a tablet that is usually taken by mouth three times a day for six weeks.
  • You can take Asacol HD either with food or on an empty stomach. If it bothers your stomach, try taking it with food.
  • The tablets have a special coating that makes them delayed-release tablets. In order to protect the special coating, you should not cut, chew, or crush the tablets.
  • Asacol HD should be taken at the same times each day to maintain an even level of the drug in your blood.
  • For the drug to work properly, you have to take it as prescribed.

Asacol HD Drug Information

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