Asacol HD Drug Interactions

Several medications are known to potentially interact with Asacol HD. For example, problems may occur if the ulcerative colitis medicine is taken together with digoxin, warfarin, thiopurine medications, or the chickenpox vaccine. These drug interactions could decrease the effectiveness of the medications or increase your risk for developing side effects.

Asacol HD Drug Information

An Overview of Asacol HD Interactions

Asacol HD^® (mesalamine) may potentially interact with a few other medicines. These medications that may lead to interactions with Asacol HD can include, but are not limited to:

Chickenpox vaccine
Digoxin (Digitek^®, Lanoxin^®)
Thiopurine medications, including:

Azathioprine (Azasan^®, Imuran^®)
Mercaptopurine (Purinethol^®)
Thioguanine (Tabloid^®)

Warfarin (Coumadin^®, Jantoven^®).

More Information on Asacol HD Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when Asacol HD is taken with any of the medications listed above.

Chickenpox Vaccine

Asacol HD is a salicylate medication. Salicylates should generally be avoided for six weeks after receiving the chickenpox vaccine, due to the risk of Reye's syndrome.

Digoxin

Asacol HD could potentially decrease the absorption of digoxin, perhaps making it less effective. Your healthcare provider may decide to monitor you more closely (and may even measure your digoxin blood levels), especially when you first start or stop taking Asacol HD.

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