Apriso Drug Interactions

Apriso Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Apriso is combined with any of the drugs listed above.
 
Antacids
Apriso should not be taken with antacids, as this may cause the mesalamine to be released in the stomach, instead of the colon (where it is intended to work).
 
Azathioprine
Apriso may decrease the body's ability to metabolize azathioprine, perhaps increasing the risk of side effects of azathioprine. Check with your healthcare provider before taking these medications together.
 
Digoxin (Digitek, Lanoxin)
Apriso may decrease the absorption of digoxin into your body, perhaps making it less effective. Your healthcare provider should monitor the level of digoxin in your blood, especially when you are starting or stopping Apriso.
 
H2 Blockers
Apriso should not be taken with H2 blockers, as this may cause the mesalamine to be released in the stomach, instead of the colon (where it is intended to work).
 
Mercaptopurine
Apriso may decrease the body's ability to metabolize mercaptopurine, perhaps increasing the risk of mercaptopurine side effects. Check with your healthcare provider before taking these medications together.
 
Proton Pump Inhibitors (PPIs)
Apriso should not be taken with PPIs, as this may cause the mesalamine to be released in the stomach, instead of the colon (where it is intended to work).
  
Thioguanine
Apriso may decrease the body's ability to metabolize thioguanine, perhaps increasing the risk of side effects of thioguanine. Check with your healthcare provider before taking these medications together.

Apriso Drug Information

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